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Molecular Profiling pp 59–77Cite as

The Human Side of Cancer Biobanking

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 823))

Abstract

The future success of translational research is critically dependent on the procurement and availability of high-quality tissue specimens linked to accurate histopathologic and clinical information about the individual banked specimen. The international community has awakened to this critical need only recently. Three major roadblocks have hindered the success of previous biobank consortiums: (1) Ethical issues surrounding patient consent and ownership of intellectual property, (2) Failure to properly preserve the molecular content of the tissue, and failure to reliably document clinical data linked to the specimen, and (3) Management issues: inadequate funding, competition for use of the tissue, inadequate personnel and facilities, and absence of dedicated database software. This chapter reviews these critical roadblocks and discusses international efforts to provide strategies to implement high-quality biobanks.

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Author information

Authors and Affiliations

  1. Department of Histopathology, Biobank Ireland Trust, St James’s Hospital, Dublin, Ireland

    Eoin F. Gaffney

  2. Faculty of Law, University College, Cork, Ireland

    Deirdre Madden

  3. Department of Surgery and Cancer, Hammersmith Hospital/Wales Cancer Bank, London, UK

    Geraldine A. Thomas

Authors
  1. Eoin F. Gaffney
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  2. Deirdre Madden
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  3. Geraldine A. Thomas
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Corresponding author

Correspondence to Eoin F. Gaffney .

Editor information

Editors and Affiliations

  1. Center for Applied Proteomics and, George Mason University, University Blvd. 10900, Manassas, 20110, Virginia, USA

    Virginia Espina

  2. Center for Applied Proteomics &, George Mason University, University Blvd. 10900, Manassas, 20110, Virginia, USA

    Lance A. Liotta

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© 2012 Springer Science+Business Media, LLC

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Gaffney, E.F., Madden, D., Thomas, G.A. (2012). The Human Side of Cancer Biobanking. In: Espina, V., Liotta, L. (eds) Molecular Profiling. Methods in Molecular Biology, vol 823. Humana Press. https://doi.org/10.1007/978-1-60327-216-2_5

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  • DOI: https://doi.org/10.1007/978-1-60327-216-2_5

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-215-5

  • Online ISBN: 978-1-60327-216-2

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