Abstract
Post-translational modification by SUMO is an important mechanism to regulate transcription. Sumoyla-tion has diverse effects on substrate activity, but in most cases reported to date sumoylation of transcription factors correlated with transcriptional repression. Here we describe general strategies to address how post-translational modification by SUMO regulates the activity of a DNA-binding transcription factor.
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Ouyang, J., Valin, A., Gill, G. (2009). Regulation of Transcription Factor Activity by SUMO Modification. In: Ulrich, H.D. (eds) SUMO Protocols. METHODS IN MOLECULAR BIOLOGY™, vol 497. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-566-4_9
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DOI: https://doi.org/10.1007/978-1-59745-566-4_9
Publisher Name: Humana Press, Totowa, NJ
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Online ISBN: 978-1-59745-566-4
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