Meiosis pp 77-97 | Cite as

Analysis of Meiotic Recombination in Caenorhabditis elegans

  • Kenneth J. Hillers
  • Anne M. Villeneuve
Part of the Methods in Molecular Biology book series (MIMB, volume 557)


Caenorhabditis elegans is an important experimental organism for the study of recombination during meiosis. A variety of techniques have been developed for the measurement of meiotic recombination in C. elegans, ranging from traditional genetic measures to direct cytological determination of chiasma frequency. Here, we provide methods for some of the varied approaches used for the study of meiotic recombination in these tiny but powerful worms.

Key words

crossing over PCR recombination chiasmata snip-SNP bivalent univalent 


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Copyright information

© Humana Press, a part of Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Kenneth J. Hillers
    • 1
  • Anne M. Villeneuve
    • 2
  1. 1.Biological SciencesCalifornia Polytechnic State UniversitySan Luis ObispoUSA
  2. 2.Department of Developmental BiologyStanford University School of MedicineStanfordUSA

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