Abstract
Multiple drug resistance to antibiotics is a major public health problem. Many mechanisms may be involved in such resistance. Increasing data have shown that Staphylococcus aureus can invade different types of nonphagocytic cells, which, in turn, may contribute to evasion of the toxicity of certain antibiotics. The fibronectin-binding proteins are required for S. aureus to adhere to and internalize into the host cells. We have shown that a two-component signal transduction system, SaeRS, is essential for bacterial adhesion and invasion of the epithelial cells.
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© 2007 Humana Press Inc., Totowa, NJ
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Liang, X., Ji, Y. (2007). Comparative Analysis of Staphylococcal Adhesion and Internalization by Epithelial Cells. In: Ji, Y. (eds) Methicillin-Resistant Staphylococcus aureus (MRSA) Protocols. Methods in Molecular Biology, vol 391. Humana Press. https://doi.org/10.1007/978-1-59745-468-1_11
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DOI: https://doi.org/10.1007/978-1-59745-468-1_11
Publisher Name: Humana Press
Print ISBN: 978-1-58829-655-9
Online ISBN: 978-1-59745-468-1
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