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Dissecting Embryonic Neural Tissues for Transplantation

  • Protocol
Neural Transplantation Methods

Part of the book series: Neuromethods ((NM,volume 36))

Abstract

A variety of sources of cells and tissues have been successfully trans-planted into the central nervous system (CNS). Thus, in the first decades of this century came the first reports of successful grafting, not only of CNS tissues (Del Conte, 1907; Dunn, 1917; Le Gros Clark, 1940) and peripheral nerves (Tello, 1911), but also of a variety of nonneuronal tissues, such as skin (Glees, 1940), neuroendocrine cells (Flerkó and Szentágothai, 1957), or tissue derived from tumors (Greene, 1943). Nevertheless, most of these techniques were relatively unreliable, and set in a context in which the Zeitgeist (influenced by Cajal’s classic studies on degeneration and regeneration in the nervous system [Cajal, 1928]) was that regeneration was essentially minimal in the CNS of mature adult mammals.

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Author information

Authors and Affiliations

  1. Department of Experimental Psychology and the Centre for Brain Repair, University of Cambridge, Cambridge, UK

    Stephen B. Dunnett

  2. School of Biosciences, Cardiff University, Wales, UK

    Stephen B. Dunnett

  3. Wallenberg Neuroscience Centre, Lund, Sweden

    Anders Björklund

Authors
  1. Stephen B. Dunnett
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  2. Anders Björklund
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Editor information

Editors and Affiliations

  1. University of Cambridge, Cambridge, UK

    Stephen B. Dunnett

  2. Cardiff University, Cardiff, Wales, UK

    Stephen B. Dunnett

  3. University of Saskatchewan, Saskatoon, Canada

    Alan A. Boulton

  4. University of Alberta, Edmonton, Canada

    Glen B. Baker

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© 2000 Humana Press Inc., Totowa, NJ

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Dunnett, S.B., Björklund, A. (2000). Dissecting Embryonic Neural Tissues for Transplantation. In: Dunnett, S.B., Boulton, A.A., Baker, G.B. (eds) Neural Transplantation Methods. Neuromethods, vol 36. Humana Press. https://doi.org/10.1007/978-1-59259-690-4_1

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  • DOI: https://doi.org/10.1007/978-1-59259-690-4_1

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-793-9

  • Online ISBN: 978-1-59259-690-4

  • eBook Packages: Springer Protocols

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