Abstract
Plasma stability of ADCs can have a profound impact on ADC efficacy and safety. LC-MS methods enable the detection and characterization of ADC to evaluate its stability in plasma. Here we describe a procedure and LC-MS method for assessing ADC plasma stability.
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References
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Wei, C. (2020). Assessing ADC Plasma Stability by LC-MS Methods. In: Tumey, L. (eds) Antibody-Drug Conjugates. Methods in Molecular Biology, vol 2078. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9929-3_25
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DOI: https://doi.org/10.1007/978-1-4939-9929-3_25
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Publisher Name: Humana, New York, NY
Print ISBN: 978-1-4939-9928-6
Online ISBN: 978-1-4939-9929-3
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