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Rodent Infections for Chlamydia spp.

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Chlamydia trachomatis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2042))

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Abstract

Chlamydia spp. infections cause immunopathology of the male and female urogenital tracts and incidence continues to rise across the globe. Animal models offer the opportunity to study the host: pathogen relationship, with rodent models being an attractive first step in studying immune interactions, genetic knockout, as well as bacterial inhibitor and vaccine trials. Here we describe the methodology to infect both male and female rodents at various mucosal sites, with a particular focus on the reproductive tracts.

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Acknowledgments

KB is supported by NHMRC grants APP1083314 and APP1062198. KB and AJC are supported by NHMRC grant APP1145825. The authors thank Emily Bryan, Logan Trim, and David Van Der Heide for their assistance. CWA and AJC contributed equally.

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Author notes

  1. Charles W. Armitage and Alison J. Carey contributed equally to this work.

Authors and Affiliations

  1. Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia

    Charles W. Armitage, Alison J. Carey & Kenneth W. Beagley

Authors
  1. Charles W. Armitage
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  2. Alison J. Carey
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  3. Kenneth W. Beagley
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Corresponding author

Correspondence to Kenneth W. Beagley .

Editor information

Editors and Affiliations

  1. Department of Microbiology and Immunology, Vet School, Cornell University, Ithaca, NY, USA

    Amanda Claire Brown

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Armitage, C.W., Carey, A.J., Beagley, K.W. (2019). Rodent Infections for Chlamydia spp.. In: Brown, A. (eds) Chlamydia trachomatis. Methods in Molecular Biology, vol 2042. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9694-0_15

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  • DOI: https://doi.org/10.1007/978-1-4939-9694-0_15

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-9693-3

  • Online ISBN: 978-1-4939-9694-0

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