Measuring Protein Solubility
Protein solubility determines the conditions under which the protein will remain in solution. As a result, it is an important quantity in applications that involve concentrated protein solutions. Here I describe the solubility measurement of the protein thaumatin in the presence of tartrate ions as a function of temperature. This method can be used to measure the solubility of other proteins.
Key wordsProtein Solubility Thaumatin Protein crystallization Phase diagrams
I gratefully acknowledge financial support from the National Science Foundation (DMR 0901260 and 1206416) and Yeshiva University.
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