Informed Consent Issues for Cell Donors

Part of the Methods in Molecular Biology book series (MIMB, volume 2005)


Stem cell-based chimera research depends on the free and voluntary provision of human biomaterials necessary for the derivation of pluripotent stem cell lines. Informed consent requirements for the procurement of human embryos, gametes, and somatic cells must take into account unique features of biomedical research involving the use of immortal cell lines that carry their donors’ genetic information. The extent and basis for donors’ rights, including the right to withdraw from research, are explored here in detail.

Key words

Informed consent Donors’ rights Research withdrawal 


  1. 1.
    International Society for Stem Cell Research (2016) Guidelines for stem cell science and clinical translation. Accessed 20 Oct 2018
  2. 2.
    National Academy of Sciences (2005) Guidelines for human embryonic stem cell research. The National Academies Press, Washington, DCGoogle Scholar
  3. 3.
    Daley GQ, Hyun I, Apperley JF et al (2016) Setting global standards for stem cell research and clinical translation: the 2016 ISSCR guidelines. Stem Cell Reports 6:787–797CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of BioethicsCase Western Reserve University, School of MedicineClevelandUSA

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