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Transplantation of Autologous Dermo-Epidermal Skin Substitutes in a Pig Model

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Skin Tissue Engineering

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1993))

Abstract

Due to its similarity of skin anatomy and physiology, the pig appears to be a well-suited animal model for preclinical studies of skin analog transplantations. The choice of the location of the skin defect and appropriate postoperative measures are essential for the protection of the transplanted graft. This protocol describes in detail a porcine skin transplantation model including peri- and postoperative measures taken to improve and refine the study outcome.

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References

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Authors and Affiliations

  1. Division of Surgical Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland

    Thea Fleischmann, Miriam Lipiski, Margarete Arras & Nikola Cesarovic

  2. Biological Central Laboratory, University of Zurich, Zurich, Switzerland

    Thea Fleischmann, Flora Nicholls & Miriam Lipiski

Authors
  1. Thea Fleischmann
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  2. Flora Nicholls
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  3. Miriam Lipiski
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  4. Margarete Arras
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  5. Nikola Cesarovic
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Corresponding author

Correspondence to Thea Fleischmann .

Editor information

Editors and Affiliations

  1. University Children’s Hospital Zurich, Zurich, Switzerland

    Sophie Böttcher-Haberzeth  & Thomas Biedermann  & 

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Fleischmann, T., Nicholls, F., Lipiski, M., Arras, M., Cesarovic, N. (2019). Transplantation of Autologous Dermo-Epidermal Skin Substitutes in a Pig Model. In: Böttcher-Haberzeth, S., Biedermann, T. (eds) Skin Tissue Engineering. Methods in Molecular Biology, vol 1993. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9473-1_20

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  • DOI: https://doi.org/10.1007/978-1-4939-9473-1_20

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-9472-4

  • Online ISBN: 978-1-4939-9473-1

  • eBook Packages: Springer Protocols

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