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Experimental Tubulogenesis Induction Model in the Mouse

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1926))

Abstract

Kidney development and induction of tubulogenesis have been studied for almost seven decades. The experimental setup of metanephric mesenchyme induction ex vivo allows to control the environment, to perform cellular manipulations, and to learn about renal development. Since the establishment of the ex vivo kidney culture technique in 1953, the method was modified to suit well the progress in biological and medical fields and still today present many advantages over the traditional in vivo studies.

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Acknowledgments

I would like to thank Sanna Junttila and Paula Haipus for producing the movies from which Figs. 1 and 2 were made.

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Correspondence to Aleksandra Rak-Raszewska .

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Rak-Raszewska, A. (2019). Experimental Tubulogenesis Induction Model in the Mouse. In: Vainio, S. (eds) Kidney Organogenesis. Methods in Molecular Biology, vol 1926. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-9021-4_4

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  • DOI: https://doi.org/10.1007/978-1-4939-9021-4_4

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-9020-7

  • Online ISBN: 978-1-4939-9021-4

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