Skip to main content
SpringerLink
Log in

Biobanking of Urine Samples

  • Protocol
  • First Online:
Biobanking

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1897))

Abstract

Urine is a major repository of biometabolites, some proteins, and DNA. Within the past few decades, it has become increasingly apparent that certain infectious, neoplastic, and congenital diseases can be investigated using urine samples for diagnostic and prognostic purposes. In this chapter, a number of pertinent urine analytes and methods of banking urine samples for future analyses are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Protocol
USD 49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Kemper FH (1993) Human organ specimen banking—15 years of experience. Sci Total Environ 139–140:13–25

    Article  Google Scholar 

  2. Jackson C, Best N, Elliott P (2008) UK Biobank Pilot Study: stability of haematological and clinical chemistry analytes. Int J Epidemiol 37(Suppl 1):i16–i22

    Article  Google Scholar 

  3. Van Noord PA (2003) Banking of urine sediments as DNA source in epidemiologic studies. Epidemiology 14:254 author reply 254–255

    Article  Google Scholar 

  4. Echeverry G, Hortin GL, Rai AJ (2010) Introduction to urinalysis: historical perspectives and clinical application. In: Rai AJ (ed) The urinary proteome methods and protocols, 1st edn. Springer, New York, pp 1–12

    Google Scholar 

  5. Hussong JW, Kjeldsberg CR (eds) (2014) Kjeldsberg’s body fluid analysis. American Society for Clinical Pathology, Chicago

    Google Scholar 

  6. Thongboonkerd V, Saetun P (2007) Bacterial overgrowth affects urinary proteome analysis: recommendation for centrifugation, temperature, duration, and the use of preservatives during sample collection. J Proteome Res 6:4173–4181

    Article  CAS  Google Scholar 

  7. Quek SI, Wong OM, Chen A et al (2015) Processing of voided urine for prostate cancer RNA biomarker analysis. Prostate 75:1886–1895

    Article  CAS  Google Scholar 

  8. Saetun P, Semangoen T, Thongboonkerd V (2009) Characterizations of urinary sediments precipitated after freezing and their effects on urinary protein and chemical analyses. Am J Physiol Renal Physiol 296:F1346–F1354

    Article  CAS  Google Scholar 

  9. Fiedler GM, Ceglarek U, Leichtle A et al (2010) Standardized preprocessing of urine for proteome analysis. In: Rai AJ (ed) The urinary proteome methods and protocols, 1st edn. Springer, New York, pp 47–63

    Chapter  Google Scholar 

  10. Jackson DH, Banks RE (2010) Banking of clinical samples for proteomic biomarker studies: a consideration of logistical issues with a focus on pre-analytical variation. Proteomics Clin Appl 4:250–270

    Article  CAS  Google Scholar 

  11. Cairns P (2004) Detection of promoter hypermethylation of tumor suppressor genes in urine from kidney cancer patients. Ann N Y Acad Sci 1022:40–43

    Article  CAS  Google Scholar 

  12. Mehta TK, Hoque MO, Ugarte R et al (2006) Quantitative detection of promoter hypermethylation as a biomarker of acute kidney injury during transplantation. Transplant Proc 38:3420–3426

    Article  CAS  Google Scholar 

  13. Roest M, van der Schouw YT, de Valk B et al (1999) Heterozygosity for a hereditary hemochromatosis gene is associated with cardiovascular death in women. Circulation 100:1268–1273

    Article  CAS  Google Scholar 

  14. Van Noord PA (1985) Epidemiological aspects of data banks and biological banks. Tijdschr Diergeneeskd 110:703–715

    PubMed  Google Scholar 

  15. Murdoch DR, Walford EJ, Jennings LC et al (1996) Use of the polymerase chain reaction to detect Legionella DNA in urine and serum samples from patients with pneumonia. Clin Infect Dis 23:475–480

    Article  CAS  Google Scholar 

  16. Cannas A, Kalunga G, Green C et al (2009) Implications of storing urinary DNA from different populations for molecular analyses. PLoS One 4:e6985

    Article  Google Scholar 

  17. Chapin KC (2006) Molecular tests for detection of the sexually-transmitted pathogens Neisseria gonorrhoeae and Chlamydia trachomatis. Med Health R I 89:202–204

    PubMed  Google Scholar 

  18. Fisa R, Riera C, Lopez-Chejade P et al (2008) Leishmania infantum DNA detection in urine from patients with visceral leishmaniasis and after treatment control. Am J Trop Med Hyg 78:741–744

    Article  Google Scholar 

  19. Mharakurwa S, Simoloka C, Thuma PE et al (2006) PCR detection of Plasmodium falciparum in human urine and saliva samples. Malar J 5:103

    Article  Google Scholar 

  20. Cannas A, Goletti D, Girardi E et al (2008) Mycobacterium tuberculosis DNA detection in soluble fraction of urine from pulmonary tuberculosis patients. Int J Tuberc Lung Dis 12:146–151

    CAS  PubMed  Google Scholar 

  21. Elliott P, Peakman TC, Biobank UK (2008) The UK Biobank sample handling and storage protocol for the collection, processing and archiving of human blood and urine. Int J Epidemiol 37:234–244

    Article  Google Scholar 

  22. Riegman PH, Morente MM, Betsou F et al (2008) Biobanking for better healthcare. Mol Oncol 2:213–222

    Article  Google Scholar 

  23. Povey S, Al Aqeel AI, Cambon-Thomsen A et al (2010) Practical guidelines addressing ethical issues pertaining to the curation of human locus-specific variation databases (LSDBs). Hum Mutat 31:1179–1184

    Article  Google Scholar 

  24. Holland NT, Smith MT, Eskenazi B et al (2003) Biological sample collection and processing for molecular epidemiological studies. Mutat Res 543:217–234

    Article  CAS  Google Scholar 

  25. Cambon-Thomsen A (2004) The social and ethical issues of post-genomic human biobanks. Nat Rev Genet 5:866–873

    Article  CAS  Google Scholar 

  26. Protections OfHR (2014) International compilation of human research standards. Services USDoHaH: http://www.hhs.gov/ohrp/international/intlcompilation/2014intlcomp.pdf.pdf

  27. Van Veen EB, Riegman PH, Dinjens WN et al (2006) TuBaFrost 3: regulatory and ethical issues on the exchange of residual tissue for research across Europe. Eur J Cancer 42:2914–2923

    Article  Google Scholar 

  28. Chabannon C, Doran P, Hofman P et al (2012) Annual conferences of the European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB): overview of 2011 and preview of 2012. Biopreserv Biobank 10:407–415

    Article  Google Scholar 

  29. Harris JR, Burton P, Knoppers BM et al (2012) Toward a roadmap in global biobanking for health. Eur J Hum Genet 20:1105–1111

    Article  Google Scholar 

  30. Mischak H, Kolch W, Aivaliotis M et al (2010) Comprehensive human urine standards for comparability and standardization in clinical proteome analysis. Proteomics Clin Appl 4:464–478

    Article  CAS  Google Scholar 

  31. Ercan M, Akbulut ED, Abusoglu S et al (2015) Stability of urine specimens stored with and without preservatives at room temperature and on ice prior to urinalysis. Clin Biochem 48:919–922

    Article  CAS  Google Scholar 

  32. Nabi G, N’Dow J, Hasan TS et al (2005) Proteomic analysis of urine in patients with intestinal segments transposed into the urinary tract. Proteomics 5:1729–1733

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA

    Neda A. Moatamed

Authors
  1. Neda A. Moatamed
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Neda A. Moatamed .

Editor information

Editors and Affiliations

  1. Division of Neuropathology, Department of Pathology and Laboratory Medicine, Brain Tumor Translational Resource, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

    William H. Yong

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Science+Business Media, LLC, part of Springer Nature

About this protocol

Check for updates. Verify currency and authenticity via CrossMark

Cite this protocol

Moatamed, N.A. (2019). Biobanking of Urine Samples. In: Yong, W. (eds) Biobanking. Methods in Molecular Biology, vol 1897. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8935-5_12

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-8935-5_12

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-8933-1

  • Online ISBN: 978-1-4939-8935-5

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics

Search

Navigation