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Analysis of Population-Genetic Properties of Copy Number Variations

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Copy Number Variants

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1833))

Abstract

While single nucleotide polymorphisms (SNPs) are typically the variant of choice for population genetics, copy number variations (CNVs) which comprise insertions, deletions and duplications of genomic sequences, is also an informative type of genetic variation. CNVs have been shown to be both common in mammals and important for understanding the relationship between genotype and phenotype. Moreover, population-specific CNVs are candidate regions under selection and are potentially responsible for diverse phenotypes.

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Change history

  • 04 September 2018

    The original version of the book was inadvertently published with incorrect spelling of the author name “Liu Yang”. The author name has now been corrected.

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Acknowledgments

This work was supported in part by Agricultural Science and Technology Innovation Program of China (ASTIP-IAS-TS-16). L.Y.X was supported by the Elite Youth Program in Chinese Academy of Agricultural Sciences.

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Xu, L., Yang, L., Bickhart, D.M., Li, J., Liu, G.E. (2018). Analysis of Population-Genetic Properties of Copy Number Variations. In: Bickhart, D. (eds) Copy Number Variants. Methods in Molecular Biology, vol 1833. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8666-8_14

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  • DOI: https://doi.org/10.1007/978-1-4939-8666-8_14

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-8665-1

  • Online ISBN: 978-1-4939-8666-8

  • eBook Packages: Springer Protocols

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