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Pre-Clinical and Clinical Methods in Brain Trauma Research pp 271–282Cite as

Dynamic Contrast-Enhanced MRI for the Analysis of Blood-Brain Barrier Leakage in Traumatic Brain Injury

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Part of the book series: Neuromethods ((NM,volume 139))

Abstract

Blood-brain barrier (BBB) could be impaired following traumatic brain injury. Here we describe a modified technique for noninvasive longitudinal assessment of the of BBB integrity based on dynamic contrast-enhanced magnetic resonance imaging technique to evaluate the longitudinal progression of BBB leakage following traumatic brain injury in rats.

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Author information

Authors and Affiliations

  1. Research Imaging Institute, UT Health San Antonio, San Antonio, TX, USA

    Qiang Shen

  2. Department of Ophthalmology, UT Health San Antonio, San Antonio, TX, USA

    Qiang Shen

  3. Department of Radiology, UT Health San Antonio, San Antonio, TX, USA

    Qiang Shen

  4. Department of Radiology, Stony Brook School of Medicine, Stony Brook, NY, USA

    Timothy Q. Duong

Authors
  1. Qiang Shen
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  2. Timothy Q. Duong
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Corresponding author

Correspondence to Qiang Shen .

Editor information

Editors and Affiliations

  1. Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Sciences Center at Houston, Houston, Texas, USA

    Amit K. Srivastava

  2. Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Sciences Center at Houston, Houston, Texas, USA

    Charles S. Cox

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Shen, Q., Duong, T.Q. (2018). Dynamic Contrast-Enhanced MRI for the Analysis of Blood-Brain Barrier Leakage in Traumatic Brain Injury. In: Srivastava, A., Cox, C. (eds) Pre-Clinical and Clinical Methods in Brain Trauma Research. Neuromethods, vol 139. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8564-7_17

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  • DOI: https://doi.org/10.1007/978-1-4939-8564-7_17

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-8563-0

  • Online ISBN: 978-1-4939-8564-7

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