Abstract
Progranulin (PGRN) has been reported to be associated with cell proliferation, cell growth, wound healing, and inflammation. PGRN mutations are known to be related to dementia. However, the association between PGRN and atherosclerosis remains to be elucidated. Therefore, we generated PGRN−/−ApoE−/− mice to analyze the effect of PGRN on the development of atherosclerosis.
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Ohama, T., Kawase, R., Sakata, Y., Yamashita, S. (2018). Methods for Studying the Function of Progranulin in Atherosclerosis Using Both Knockout Mice Models and In Vitro Studies. In: Bateman, A., Bennett, H., Cheung, S. (eds) Progranulin. Methods in Molecular Biology, vol 1806. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8559-3_21
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DOI: https://doi.org/10.1007/978-1-4939-8559-3_21
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Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-8557-9
Online ISBN: 978-1-4939-8559-3
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