HLA Typing pp 11-29 | Cite as

Role of Human Leukocyte Antigens (HLA) in Autoimmune Diseases

  • Gergely Bodis
  • Victoria Toth
  • Andreas SchwartingEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1802)


The aim of this review is to provide a brief overview of the role and current clinical relevance of HLA-B27 in spondyloarthritis and HLA-B51 in Behcet’s disease as well as HLA-DQ2/DQ8 in celiac disease and HLA-DRB1 in rheumatoid arthritis and to discuss possible future implications.


Spondyloarthritis Behcet’s disease Rheumatoid arthritis Autoimmunity HLA-B27 HLA-B51 HLA-DQ2/DQ8m HLA-DRB1 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Gergely Bodis
    • 1
    • 2
  • Victoria Toth
    • 1
    • 2
  • Andreas Schwarting
    • 2
    • 3
    Email author
  1. 1.Bioscientia Institut für Medizinische Diagnostik GmbHIngelheimGermany
  2. 2.Acura Rheumatology Center Rhineland PalatineBad KreuznachGermany
  3. 3.Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IUniversity Medical Center of the Johannes Gutenberg University MainzMainzGermany

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