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Psychoneuroimmunology pp 309–326Cite as

The Vaccination Model in Psychoneuroimmunology Research: A Review

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1781))

Abstract

This chapter explores the reasoning behind using the vaccination model to examine the influence of psychosocial factors on immunity. It then briefly discusses the mechanics of the vaccination response and the protocols used in psychoneuroimmunology vaccine research, before giving examples from the research literature of the studies examining relationships such as the association between stress and vaccination response. It also explores the ways the vaccination model can be used to answer key questions in psychoneuroimmunology, such as the following: “Does it matter when stressful life events occur relative to when the vaccine is received?” “What are the effects of prior exposure to the antigen?” “Do other psychosocial factors influence vaccine response besides stress?” Finally, it briefly considers the mechanisms underlying psychosocial factors and vaccination response associations and the future research needed to understand these better, and indeed to use current and future knowledge to improve and enhance vaccine responses in key at-risk populations.

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  1. School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK

    Anna C. Whittaker

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  1. Anna C. Whittaker
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Correspondence to Anna C. Whittaker .

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  1. University of Maryland University College, Adelphi, MD, PharmTao, Santa Clara, California, USA

    Qing Yan

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Whittaker, A.C. (2018). The Vaccination Model in Psychoneuroimmunology Research: A Review. In: Yan, Q. (eds) Psychoneuroimmunology. Methods in Molecular Biology, vol 1781. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7828-1_16

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  • DOI: https://doi.org/10.1007/978-1-4939-7828-1_16

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