Chromothripsis pp 279-289 | Cite as

ChromothripsisDB: A Curated Database for the Documentation, Visualization, and Mining of Chromothripsis Data

  • Haoyang Cai
Part of the Methods in Molecular Biology book series (MIMB, volume 1769)


ChromothripsisDB ( is a manually curated database containing a unified description of published chromothripsis cases and relevant genomic aberrations. Available data includes copy number alterations, chromosome structural variations, and gene annotations. The criteria used for detecting chromothripsis in each study are also provided. At present, the molecular mechanisms involved in chromothripsis phenomenon are not fully understood. Thus, further studies with large number of identified chromothripsis samples are needed. The current release of ChromothripsisDB contains more than 400 patient samples, representing over 100 research articles. It represents an extraordinary resource for mining the existing knowledge of chromothripsis.


Database Copy number alteration Chromosome structural variation Genomic aberration Cancer genome Data mining 



This work was funded by the National Natural Science Foundation of China [grant numbers 31571314 and U1603120].


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resources and Eco-EnvironmentCollege of Life Sciences, Sichuan UniversityChengduChina

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