Abstract
Colorectal cancer is the most common gastrointestinal cancer and the second-most common cause of cancer-related death worldwide. Microparticles are small vesicles known to be implicated in tumor growth, the development of metastases, and cancer-associated procoagulant activity. We have reported a specific hallmark of microparticles in colorectal and pancreatic cancers, the so-called “microparticulosome.” We have also reported on variations in the microparticulosome in the case of the occurrence of a thromboembolic event. Here, we describe our flow cytometry-based methods for identifying and characterizing tumor-derived microparticles and thereby monitoring colorectal cancer evolution.
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Mege, D., Panicot-Dubois, L., Dubois, C. (2018). Tumor-Derived Microparticles to Monitor Colorectal Cancer Evolution. In: Beaulieu, JF. (eds) Colorectal Cancer. Methods in Molecular Biology, vol 1765. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7765-9_17
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DOI: https://doi.org/10.1007/978-1-4939-7765-9_17
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Publisher Name: Humana Press, New York, NY
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