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3D Sponge-Matrix Histoculture pp 1–9Cite as

In Memoriam: Joseph Leighton, 1921–1999—Father of 3-Dimensional Tissue Culture

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Part of the Methods in Molecular Biology book series (MIMB,volume 1760)

Abstract

Joseph Leighton developed sponge-matrix histoculture in the early 1950s and is the father of true 3D cell and tissue culture. Dr. Leighton demonstrated that sponge-matrix histoculture could replicate in vivo-like tissue structure and function by allowing cells to take their natural shape.

Key words

  • Sponge-matrix
  • 3-Dimensional
  • Histoculture
  • Tumors
  • Cell-self-organization
  • Organoid
  • Tissue

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  • DOI: 10.1007/978-1-4939-7745-1_1
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References

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Authors and Affiliations

  1. AntiCancer, Inc., San Diego, CA, USA

    Robert M. Hoffman

  2. Department of Surgery, UCSD, San Diego, CA, USA

    Robert M. Hoffman

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  1. Robert M. Hoffman
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Correspondence to Robert M. Hoffman .

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Editors and Affiliations

  1. AntiCancer, Inc., San Diego, California, USA

    Dr. Robert M. Hoffman

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Hoffman, R.M. (2018). In Memoriam: Joseph Leighton, 1921–1999—Father of 3-Dimensional Tissue Culture. In: Hoffman, R. (eds) 3D Sponge-Matrix Histoculture. Methods in Molecular Biology, vol 1760. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7745-1_1

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  • DOI: https://doi.org/10.1007/978-1-4939-7745-1_1

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7743-7

  • Online ISBN: 978-1-4939-7745-1

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