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A Primer for the Rat Genome Database (RGD)

  • Stanley J. F. LaulederkindEmail author
  • G. Thomas Hayman
  • Shur-Jen Wang
  • Jennifer R. Smith
  • Victoria Petri
  • Matthew J. Hoffman
  • Jeff De Pons
  • Marek A. Tutaj
  • Omid Ghiasvand
  • Monika Tutaj
  • Jyothi Thota
  • Melinda R. Dwinell
  • Mary Shimoyama
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1757)

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.

Key words

Rat Database Quantitative trait locus Ontology Genomics Gene 

Notes

Acknowledgments

RGD is supported by the National Heart, Lung, and Blood Institute on behalf of the National Institutes of Health [HL64541].

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Stanley J. F. Laulederkind
    • 1
    Email author
  • G. Thomas Hayman
    • 1
  • Shur-Jen Wang
    • 1
  • Jennifer R. Smith
    • 1
  • Victoria Petri
    • 1
  • Matthew J. Hoffman
    • 2
    • 3
  • Jeff De Pons
    • 1
  • Marek A. Tutaj
    • 1
  • Omid Ghiasvand
    • 1
  • Monika Tutaj
    • 1
  • Jyothi Thota
    • 1
  • Melinda R. Dwinell
    • 2
    • 3
  • Mary Shimoyama
    • 1
  1. 1.Department of Biomedical EngineeringMedical College of Wisconsin and Marquette UniversityMilwaukeeUSA
  2. 2.Genomic Sciences and Precision Medicine CenterMedical College of WisconsinMilwaukeeUSA
  3. 3.Department of PhysiologyMedical College of WisconsinMilwaukeeUSA

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