Electrotaxis: Cell Directional Movement in Electric Fields
Electrotaxis plays an important role during embryogenesis, inflammation, wound healing, and tumour metastasis. However, the mechanisms at play during electrotaxis are still poorly understood. Therefore intensive studies on signaling pathways involved in this phenomenon should be carried out. In this chapter, we described an experimental system for studying electrotaxis of Amoeba proteus, mouse embryonic fibroblasts (MEF), Walker carcinosarcoma cells WC256, and bone marrow adherent cells (BMAC).
Key wordsElectric field Electrotaxis Galvanotaxis Electrotactic chamber Time-lapse videomicroscopy
This work was supported by a grant from the National Science Centre 2012/07/B/NZ3/02909, Poland. Faculty of Biochemistry, Biophysics, and Biotechnology of Jagiellonian University is a partner of the Leading National Research Center (KNOW) supported by the Ministry of Science and Higher Education.
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