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Spared Nerve Injury as a Long-Lasting Model of Neuropathic Pain

Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1727)

Abstract

This chapter describes surgical procedures for the induction of neuropathic pain using an animal model (rat or mouse) of spared nerve injury. In addition to technical details of the surgical technique, details of anesthesia and perioperative care are also included.

Key words

Spared nerve injury model Neuropathic pain Surgery Pain behavior Mouse Rat 

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Copyright information

© Springer Science+Business Media, LLC 2018

Authors and Affiliations

  1. 1.Division of Pharmacology, Department of Experimental MedicineUniversity of Campania “L. Vanvitelli”NaplesItaly

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