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Spared Nerve Injury as a Long-Lasting Model of Neuropathic Pain

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Neurotrophic Factors

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1727))

Abstract

This chapter describes surgical procedures for the induction of neuropathic pain using an animal model (rat or mouse) of spared nerve injury. In addition to technical details of the surgical technique, details of anesthesia and perioperative care are also included.

Serena Boccella and Francesca Guida share the first Authorship.

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Author information

Authors and Affiliations

  1. Division of Pharmacology, Department of Experimental Medicine, University of Campania “L. Vanvitelli”, Naples, Italy

    Serena Boccella, Francesca Guida, Enza Palazzo, Ida Marabese, Vito de Novellis, Sabatino Maione & Livio Luongo

Authors
  1. Serena Boccella
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  2. Francesca Guida
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  3. Enza Palazzo
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  4. Ida Marabese
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  5. Vito de Novellis
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  6. Sabatino Maione
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  7. Livio Luongo
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Corresponding author

Correspondence to Livio Luongo .

Editor information

Editors and Affiliations

  1. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy

    Stephen D. Skaper

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Boccella, S. et al. (2018). Spared Nerve Injury as a Long-Lasting Model of Neuropathic Pain. In: Skaper, S. (eds) Neurotrophic Factors. Methods in Molecular Biology, vol 1727. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7571-6_28

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  • DOI: https://doi.org/10.1007/978-1-4939-7571-6_28

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7570-9

  • Online ISBN: 978-1-4939-7571-6

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