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Real-Time Blood Pressure Recording Using Radiotelemetry in a Rat Model of Preeclampsia

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Preeclampsia

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1710))

Abstract

Radiotelemetry is increasingly being recognized not just as the gold standard but a necessity for validation of gestational hypertension seen in preeclampsia. Here we describe radiotelemetry probe implantation into the descending aorta of Sprague-Dawley rats to allow real-time blood pressure recording over the entire gestational period. This is a valuable tool to be able to track changes in maternal blood pressure throughout gestation and the efficacy of novel therapeutic agents in controlling hypertension.

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References

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Authors and Affiliations

  1. Hudson Institute of Medical Research, Clayton, VIC, 3168, Australia

    Bryan Leaw & Seshini Gurusinghe

  2. Maternal Fetal Medicine Unit, Department of Obstetrics & Gynaecology, Monash Medical Centre, Monash Health & Monash University, 246 Clayton Road, Clayton, VIC, 3168, Australia

    Rebecca Lim & Euan M. Wallace

Authors
  1. Bryan Leaw
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  2. Seshini Gurusinghe
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  3. Rebecca Lim
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  4. Euan M. Wallace
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Corresponding author

Correspondence to Bryan Leaw .

Editor information

Editors and Affiliations

  1. Monash Medical Centre, Monash University, Clayton, Victoria, Australia

    Padma Murthi

  2. INRS-Institut Armand-Frappier, Laval, Québec, Canada

    Cathy Vaillancourt

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Leaw, B., Gurusinghe, S., Lim, R., Wallace, E.M. (2018). Real-Time Blood Pressure Recording Using Radiotelemetry in a Rat Model of Preeclampsia. In: Murthi, P., Vaillancourt, C. (eds) Preeclampsia . Methods in Molecular Biology, vol 1710. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7498-6_26

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  • DOI: https://doi.org/10.1007/978-1-4939-7498-6_26

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7497-9

  • Online ISBN: 978-1-4939-7498-6

  • eBook Packages: Springer Protocols

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