Generation of Janus Molecularly Imprinted Polymer Particles

Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1575)

Abstract

Janus particles, which have two or more distinct physical surfaces, provide a number of potential applications in many fields. However, it is difficult to selectively load chemical or biological components onto the Janus particles. Here, the approach utilizing molecular imprinting and Pickering emulsion technologies for the synthesis of molecularly imprinted polymer (MIP)-based Janus particles (which showed high affinity to the targets) is described stepwise. As self-propelled microengines possessing specific molecular recognition ability, Janus molecularly imprinted polymer particles show high potential for specific and well-controlled drug delivery.

Key words

Janus particles Molecular imprinting Pickering emulsion Self-propelled microengine Drug delivery Colloidosomes 

Notes

Acknowledgment

This work was supported by the Fundamental Research Funds for the Central Universities in China (2015YGYL024).

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Copyright information

© Springer Science+Business Media LLC 2017

Authors and Affiliations

  1. 1.Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina
  2. 2.School of PharmacyUniversity of OsloBlindernNorway
  3. 3.Division of Pure and Applied BiochemistryLund UniversityLundSweden

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