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Biomedical Nanotechnology pp 73–89Cite as

Preparation of Magnetic Nanoparticles for Biomedical Applications

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1570))

Abstract

Magnetic nanoparticles have obtained great attention in the field of biomedicine in recent years owing to their excellent biocompatibility, unique magnetic properties, and ease of functionalization. Potential applications for functionalized magnetic nanoparticles span biomedical imaging, treatment via magnetic hyperthermia, drug delivery, and biosensing. This chapter provides detailed procedures for the synthesis, PEGylation, and bioconjugation of monodispersed Fe3O4 nanoparticles, hollow Fe3O4 nanoparticles, porous hollow Fe3O4 nanoparticles, and dumbbell-like Au-Fe3O4 nanoparticles. We hope this article can help readers design and reproducibly prepare high-quality magnetic nanoparticles with their specific goals in mind.

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Author information

Authors and Affiliations

  1. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 261005, China

    Xiaolian Sun

  2. Department of Chemistry, Brown University, Box H, 324 Brooke Street, Providence, RI, 02912, USA

    Shouheng Sun

Authors
  1. Xiaolian Sun
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  2. Shouheng Sun
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Corresponding author

Correspondence to Shouheng Sun .

Editor information

Editors and Affiliations

  1. Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, Illinois, USA

    Sarah Hurst Petrosko

  2. Department of Biomedical Engineering, University of Delaware, Newark, Delaware, USA

    Emily S. Day

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Sun, X., Sun, S. (2017). Preparation of Magnetic Nanoparticles for Biomedical Applications. In: Petrosko, S., Day, E. (eds) Biomedical Nanotechnology. Methods in Molecular Biology, vol 1570. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6840-4_5

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  • DOI: https://doi.org/10.1007/978-1-4939-6840-4_5

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6838-1

  • Online ISBN: 978-1-4939-6840-4

  • eBook Packages: Springer Protocols

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