Abstract
In the last years, life-threatening fungal diseases have increased significantly, due to the rising number of human individuals susceptible to fungal infections, which are in part complicated by the emergence of antifungal drug-resistant pathogens. Among yeasts, Candida albicans and Candida glabrata are the most common organisms responsible for invasive fungal diseases. The molecular detection of echinocandin resistance in Candida species may represent a useful means of monitoring the incidence of clinical isolates with antifungal resistance-associated gene alterations. Here, we describe the current methods that enable researchers and/or clinical microbiologists to accurately detect echinocandin-resistant isolates of C. albicans and C. glabrata.
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Posteraro, B., Vella, A., De Carolis, E., Sanguinetti, M. (2017). Molecular Detection of Resistance to Echinocandins. In: Lion, T. (eds) Human Fungal Pathogen Identification. Methods in Molecular Biology, vol 1508. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6515-1_23
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DOI: https://doi.org/10.1007/978-1-4939-6515-1_23
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Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-6513-7
Online ISBN: 978-1-4939-6515-1
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