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The Use of Anti-inflammatory Drugs in Epilepsy

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Antiepileptic Drug Discovery

Part of the book series: Methods in Pharmacology and Toxicology ((MIPT))

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Abstract

Epilepsy is a brain disorder associated with neuroinflammation. Furthermore, it is known that important elements of the inflammatory process increase the susceptibility to epileptic activity. Therefore, the search of pharmacological strategies focused on decreasing both neuroinflammation and neuronal excitability associated with epilepsy is important. This chapter is a review of several drugs that may be used for this purpose.

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Acknowledgments

We thank Francia Carmona for their technical assistance and the National Council for Sciences and Technology of Mexico for the support provided for developing this study (grant 220365 and scholarship 380140).

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Authors and Affiliations

  1. Department of Pharmacobiology, Center for Research and Advanced Studies, Calz. Tenorios 235, Col. Granjas Coapa, Tlalpan, Mexico City, 14330, Mexico

    María Guadalupe Valle-Dorado & Luisa Rocha

  2. Department of Physiology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

    Laura Elena Córdova-Dávalos & Rosalinda Guevara-Guzmán

  3. Plan of Combined Studies in Medicine (PECEM), Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

    Daniel Pérez-Pérez

Authors
  1. María Guadalupe Valle-Dorado
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  2. Laura Elena Córdova-Dávalos
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  3. Daniel Pérez-Pérez
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  4. Rosalinda Guevara-Guzmán
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  5. Luisa Rocha
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Corresponding author

Correspondence to María Guadalupe Valle-Dorado .

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Editors and Affiliations

  1. Laboratorio de Investigación y Desarrollo de Bioactivos (LIDeB) Faculty of Exact Sciences, National University of La Plata, La Plata, Buenos Aires, Argentina

    Alan Talevi

  2. Department of Pharmacobiology, Center for Research and Advanced Studies, Mexico City, Mexico

    Luisa Rocha

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Valle-Dorado, M.G., Córdova-Dávalos, L.E., Pérez-Pérez, D., Guevara-Guzmán, R., Rocha, L. (2016). The Use of Anti-inflammatory Drugs in Epilepsy. In: Talevi, A., Rocha, L. (eds) Antiepileptic Drug Discovery. Methods in Pharmacology and Toxicology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6355-3_2

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  • DOI: https://doi.org/10.1007/978-1-4939-6355-3_2

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6353-9

  • Online ISBN: 978-1-4939-6355-3

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