Statistical Analysis of fMRI Data

  • Mark W. WoolrichEmail author
  • Christian F. Beckmann
  • Thomas E. Nichols
  • Stephen M. Smith
Part of the Neuromethods book series (NM, volume 119)


fMRI is a powerful tool used in the study of brain function. It can noninvasively detect signal changes in areas of the brain where neuronal activity is varying. This chapter is a comprehensive description of the various steps in the statistical analysis of fMRI data. This will cover topics such as the general linear model (including orthogonality, hemodynamic variability, noise modeling, and the use of contrasts), multisubject statistics, and statistical thresholding (including random field theory and permutation methods).

Key words

fMRI Analysis Statistics General linear model Multisubject statistics Statistical thresholding 


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Mark W. Woolrich
    • 1
    Email author
  • Christian F. Beckmann
    • 1
  • Thomas E. Nichols
    • 1
  • Stephen M. Smith
    • 1
  1. 1.Oxford University Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB)John Radcliffe HospitalOxfordUK

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