Menopausal Symptoms and the Kampo Medicine: Tokishakuyakusan, Kamishoyosan, and Keishibukuryogan

  • Masakazu TerauchiEmail author
  • Toshiro Kubota
Part of the Methods in Pharmacology and Toxicology book series (MIPT)


Women in the menopausal transition and the postmenopausal period are affected with variety of physical and psychological symptoms. In a recent series of studies, we investigated the effects of three major Kampo formulae (Tokishakuyakusan, Kamishoyosan, and Keishibukuryogan) on Japanese peri- and postmenopausal women, and reached the following conclusions: (1) Each of the three formulae alleviates sleep disturbances, with Kamishoyosan the most effective in improving difficulty in initiating sleep and nonrestorative sleep; (2) Keishibukuryogan lowered the systolic and diastolic blood pressures, the pulse rate, and the resting energy expenditure of women with hypertension or high-normal blood pressure; and (3) Tokishakuyakusan could be an effective treatment for the women with both headaches and depression.

Key words

Menopause Postmenopause Sleep disorder Insomnia Blood pressure Hypertension Headache Depression 


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Department of Women’s HealthTokyo Medical and Dental UniversityBunkyoJapan
  2. 2.Department of Obstetrics and GynecologyTokyo Medical and Dental UniversityBunkyoJapan

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