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Dendritic Cell Protocols pp 3–15Cite as

Review of Mouse and Human Dendritic Cell Subsets

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1423))

Abstract

Dendritic cells are specialized antigen-presenting cells that initiate and orient immune responses. Numerous studies in mice and humans have shown that dendritic cells are heterogeneous and comprise several subsets that can be distinguished by their surface phenotype, ontogeny, and molecular signature. This review gives an overview of mouse and human dendritic cell subsets and their defining features and summarizes the current knowledge of dendritic cell subsets’ functional specialization in terms of antigen presentation.

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Acknowledgments

This work is supported by INSERM, the European Research Council, LabEx DCBiol, and Ligue contre le Cancer .

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Authors and Affiliations

  1. Institut Curie, 26 rue d’Ulm, 75248, Paris Cedex 05, France

    Elodie Segura

  2. INSERM U932, 26 rue d’Ulm, 75248, Paris Cedex 05, France

    Elodie Segura

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  1. Elodie Segura
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Correspondence to Elodie Segura .

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Editors and Affiliations

  1. Pavillon Pasteur, Institut Curie INSERM U932, Paris Cedex 05, France

    Elodie Segura

  2. Department of Biodefense, Tokyo Medical and Dental University, Tokyo, Japan

    Nobuyuki Onai

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Segura, E. (2016). Review of Mouse and Human Dendritic Cell Subsets. In: Segura, E., Onai, N. (eds) Dendritic Cell Protocols. Methods in Molecular Biology, vol 1423. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3606-9_1

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  • DOI: https://doi.org/10.1007/978-1-4939-3606-9_1

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