Abstract
Throughout their lifetime RNA molecules interact with a variety of RNA-binding proteins (RBPs). RBPs control gene expression by regulating splicing, polyadenylation, editing, transport, stability, and translation of RNA. There are ~1500 RBPs encoded by the human genome and recent studies have detected ~1100 proteins directly interacting with polyadenylated RNA. Identifying the RNAs bound by RBPs will continue to provide important insights into the regulation of gene expression.
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Wessels, HH., Hirsekorn, A., Ohler, U., Mukherjee, N. (2016). Identifying RBP Targets with RIP-seq. In: Dassi, E. (eds) Post-Transcriptional Gene Regulation. Methods in Molecular Biology, vol 1358. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3067-8_9
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DOI: https://doi.org/10.1007/978-1-4939-3067-8_9
Publisher Name: Humana Press, New York, NY
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