Arginyltransferase: A Personal and Historical Perspective

  • Richard L. SofferEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1337)


In the late 1960s and early 1970s, characterization of arginylation has been spearheaded via biochemical studies that enabled the first characterization of ATE1 and its substrate specificity. This essay summarized the recollections and insights from the era of research that followed from the original discovery of arginylation and led up to the identification of the arginylation enzyme.

Key words

Arginyltransferase Specificity of arginylation Early studies of arginylation 



I was fortunate to have very able students and fellows who shared my interest in aminoacyl transferases. They were, in alphabetical order, Charles E. Deutch, Hiroo Horinishi, Michael J. Leibowitz, Margaret Savage, and Richard C. Scarpulla.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Weill Medical CollegeCornell UniversityNew YorkUSA

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