Abstract
In recent years, many research activities have focused on Natural Products (NPs) derived from Traditional Chinese medicines (TCMs), thus making a renaissance in the drug discovery process of TCMs. Maximizing the diversity of extracts from those plants is the key for the chemical biology process. Methods for the preparation and pretreatment of plant extracts are very important for further purification and discovery of active compounds present in minor quantities. In this chapter, two methods of extraction, including one of the most broadly applicable method (solvent extraction) and one newly developed technique (supercritical fluid extraction), have been described in detail.
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Acknowledgement
This work was supported in part by the National Program on Key Basic Research Project (973 program, 2013CB734000), the National Natural Science Foundation of China (81102369, 30901849, 30911120483, 81102356, 30973665, 30911120484), the CAS Pillar Program (XDA04074000), the Ministry of Science and Technology of China (2013ZX10005004, 2011ZX11102-011-11, and 2007DFB31620), Genzyme, a Sanofi company, the Institute for Molecular Bioscience, the European Union’s Seventh Framework Programme (FP7/2007–2013) under grant agreement no. 312184. L. Z. is an Awardee of the National Distinguished Young Scholar Program in China.
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Zhang, J., Han, J., Oyeleye, A., Liu, M., Liu, X., Zhang, L. (2015). Extraction Methods of Natural Products from Traditional Chinese Medicines. In: Hempel, J., Williams, C., Hong, C. (eds) Chemical Biology. Methods in Molecular Biology, vol 1263. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2269-7_14
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DOI: https://doi.org/10.1007/978-1-4939-2269-7_14
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