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Automated Structure Determination from NMR Spectra

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Structural Proteomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1261))

Abstract

Three-dimensional structures of proteins in solution can be calculated on the basis of conformational restraints derived from NMR measurements. This chapter gives an overview of the computational methods for NMR protein structure analysis highlighting recent automated methods for the assignment of NMR spectra, the collection of conformational restraints, and the structure calculation.

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Authors and Affiliations

  1. Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany

    Elena Schmidt & Peter Güntert

  2. Frankfurt Institute of Advanced Studies, 60438, Frankfurt am Main, Germany

    Elena Schmidt & Peter Güntert

  3. Graduate School of Science and Engineering, Tokyo Metropolitan University, Hachioji, Tokyo, 192-0397, Japan

    Peter Güntert

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  1. Elena Schmidt
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  2. Peter Güntert
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Correspondence to Peter Güntert .

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Editors and Affiliations

  1. Oxford Protein Production Facility UK, Didcot, Oxfordshire, United Kingdom

    Raymond J. Owens

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Schmidt, E., Güntert, P. (2015). Automated Structure Determination from NMR Spectra. In: Owens, R. (eds) Structural Proteomics. Methods in Molecular Biology, vol 1261. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2230-7_16

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  • DOI: https://doi.org/10.1007/978-1-4939-2230-7_16

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2229-1

  • Online ISBN: 978-1-4939-2230-7

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