Skip to main content

Intraoperative Frozen Section Consultation in Gynecologic Pathology

  • Protocol
  • First Online:
Histopathology

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1180))

Abstract

Intraoperative consultation (IOC) in gynecologic pathology is aimed at providing or confirming the diagnosis at the time of surgery and evaluating the extent of disease in order to assist the surgeon in determining the surgical procedure being performed. This chapter discusses the main indications for IOC in gynecologic pathology and describes how to submit and process these specimens in order to obtain optimal material. In addition, diagnostic pitfalls and ancillary testing related to IOC in gynecologic pathology are summarized.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Protocol
USD 49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Lester SC (2010) Manual of surgical pathology. Elsevier Saunders, Philadelphia

    Google Scholar 

  2. Moodley M, Bramdev A (2005) Frozen section: its role in gynecological oncology. J Obstet Gynaecol 25:629–634

    Article  CAS  PubMed  Google Scholar 

  3. Weissman SM, Weiss SM, Newlin AC (2012) Genetic testing by cancer site: ovary. Cancer J 18:320–327

    Article  PubMed  Google Scholar 

  4. Baker P, Oliva E (2008) A practical approach to intraoperative consultation in gynecologic pathology. Int J Gynecol Pathol 27:353–365

    Article  PubMed  Google Scholar 

  5. Acs G (2002) Intraoperative consultation in gynecologic pathology. Semin Diagn Pathol 19:237–254

    PubMed  Google Scholar 

  6. Medeiros F, Muto M, Lee Y et al (2006) The tubal fimbria is a preferred site for early adenocarcinoma in patients with familial ovarian cancer syndrome. Am J Surg Pathol 30:230–236

    Article  PubMed  Google Scholar 

  7. Chiang S, Ali R, Melnyk N (2011) Frequency of known gene rearrangements in endometrial stromal tumors. Am J Surg Pathol 35: 1364–1372

    Article  PubMed  Google Scholar 

  8. Levy G, Hill MJ, Beall S (2012) Leiomyoma: genetics, assisted reproduction, pregnancy and therapeutic advances. J Assist Reprod Genet 29:703–771

    Article  PubMed Central  PubMed  Google Scholar 

  9. Köbel M, Gilks CB, Huntsman DG (2009) Adult-type granulosa cell tumors and FOXL2 mutation. Cancer Res 69:9160–9162

    Article  PubMed  Google Scholar 

  10. Medeiros F, Erickson-Johnson M, Keeney GL et al (2007) Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tract. Genes Chromosomes Cancer 46:981–990

    Article  CAS  PubMed  Google Scholar 

  11. Medeiros F, Araujo AR, Erickson-Johnson MR et al (2010) HMGA1 and HMGA2 rearrangements in mass-forming endometriosis. Genes Chromosomes Cancer 49:630–634

    CAS  PubMed  Google Scholar 

  12. Ronnett BM, DeScipio C, Murphy KM (2011) Hydatiform moles: ancillary techniques to refine diagnosis. Int J Gynecol Pathol 30:101–116

    Article  PubMed  Google Scholar 

  13. Lee KR, Young RH (2003) The distinction between primary and metastatic mucinous carcinomas of the ovary: gross and histologic findings in 50 cases. Am J Surg Pathol 27: 281–292

    Article  PubMed  Google Scholar 

  14. Zaino R, Whitney C, Brady MF et al (2001) Simultaneously detected endometrial and ovarian carcinomas: a gynecology oncology group study. Gynecol Oncol 83:355–362

    Article  CAS  PubMed  Google Scholar 

  15. Daniels MS (2012) Genetic testing by cancer site: uterus. Cancer J 18:338–342

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fabiola Medeiros M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media, New York

About this protocol

Cite this protocol

Medeiros, F., Felix, J.C. (2014). Intraoperative Frozen Section Consultation in Gynecologic Pathology. In: Day, C. (eds) Histopathology. Methods in Molecular Biology, vol 1180. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1050-2_11

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1050-2_11

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1049-6

  • Online ISBN: 978-1-4939-1050-2

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics