Genome-Scale Metabolic Models of Yeast, Methods for Their Reconstruction, and Other Applications

  • Sergio BordelEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1152)


Here, we present the concept of genome-scale metabolic models and some of their applications in metabolic engineering of yeast and in the analysis of gene expression data. The yeast species for which there are available genome-scale metabolic models are reviewed, as well as the methods for the reconstruction of genome-scale metabolic models for new species. Some commonly used algorithms for metabolic engineering and data integration are described.

Key words

Metabolic engineering Gene expression Metabolic networks Data integration 


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Copyright information

© Springer Science+Business Media, LLC 2014

Authors and Affiliations

  1. 1.Department of Chemical and Biological EngineeringChalmers University of TechnologyGothenburgSweden

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