Animal Models to Evaluate Bacterial Biofilm Development
Medical biofilms have attracted substantial attention especially in the past decade. Animal models are contributing significantly to understand the pathogenesis of medical biofilms. In addition, animal models are an essential tool in testing the hypothesis generated from clinical observations in patients and preclinical testing of agents showing in vitro antibiofilm effect. Here, we describe three animal models — two non-foreign body Pseudomonas aeruginosa biofilm models and a foreign body Staphylococcus aureus model.
Key wordsChronic lung infection Chronic wound infection Pseudomonas aeruginosa Staphylococcus aureus Animal models
Mark Shirtliff contributed fully as a co-author for this chapter and should be regarded as such.