In Vivo Electroporation-Mediated Gene Delivery to the Beating Heart
Gene therapy may represent a promising alternative strategy for cardiac muscle regeneration. In vivo electroporation, a physical method of gene transfer, has recently evolved as an efficient method for gene transfer. Here, we describe two protocols involving in vivo electroporation for gene transfer to the beating heart.
Key wordsGene transfer Electroporation Heart
This work was supported by the Olga Mayenfisch Foundation Zürich, Switzerland, and two grants from the Swiss National Science Foundation (3200-068304 and 31000-118270/1). The authors would like to thank Mrs Laura Seidel for English and administrative assistance.