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Discovery of Mitochondrial Ribosomes

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The Mitoribosome

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2661))

Abstract

In this introductory chapter, I will briefly describe how I came to discover the mammalian mitoribosome and will add a few notes on my contribution to the field.

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References

  1. O’Brien TW, Kalf GF (1967) Ribosomes from rat liver mitochondria. I. Isolation procedure and contamination studies. J Biol Chem 242(9):2172–2179

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  2. O’Brien TW, Kalf GF (1967) Ribosomes from rat liver mitochondira. II. Partial characterization. J Biol Chem 242(9):2180–2185

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  3. O’Brien TW (1971) The general occurrence of 55 S ribosomes in mammalian liver mitochondria. J Biol Chem 246(10):3409–3417

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  6. O’Brien TW (1964) Electron microscopic study of the in vivo changes in rat liver mitochondria after thyroidectomy and thyroxin administration. Dissertation, Marquette University, Milwaukee, Wisconsin

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  8. Matthews DE, Hessler RA, O’Brien TW (1978) Rapid evolutionary divergence of proteins in mammalian mitochondrial ribosomes. FEBS Lett 86(1):76–80. https://doi.org/10.1016/0014-5793(78)80102-1

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, USA

    Thomas W. O’Brien

Authors
  1. Thomas W. O’Brien
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Corresponding author

Correspondence to Thomas W. O’Brien .

Editor information

Editors and Affiliations

  1. Miller School of Medicine, University of Miami, Miami, FL, USA

    Antoni Barrientos

  2. Miller School of Medicine, University of Miami, Miami, FL, USA

    Flavia Fontanesi

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© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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O’Brien, T.W. (2023). Discovery of Mitochondrial Ribosomes. In: Barrientos, A., Fontanesi, F. (eds) The Mitoribosome. Methods in Molecular Biology, vol 2661. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3171-3_1

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  • DOI: https://doi.org/10.1007/978-1-0716-3171-3_1

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3170-6

  • Online ISBN: 978-1-0716-3171-3

  • eBook Packages: Springer Protocols

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