Abstract
Cytotoxicity test is defined as the screening test and biological evaluation of tissue cells in vitro to detect the growth, the reproduction, and also the morphological effects of the cell by use of medical devices. It is performed in vitro for determining whether that particular medical device can cause death of a cell either by direct contact or leaching of several toxic substances. Cytotoxicity assays measure the loss of some cellular and intercellular functions or structures involving lethal cytotoxicity. They also indicate whether they cause both cell and tissue injury. These assays are conducted on several bacteria including Actinomycetes as 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) proliferation assay against several cell lines to observe their cytotoxicity level.
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References
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Mondal, H., Thomas, J., Amaresan, N. (2023). Cytotoxicity Assay. In: Thomas, J., Amaresan, N. (eds) Aquaculture Microbiology. Springer Protocols Handbooks. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3032-7_25
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DOI: https://doi.org/10.1007/978-1-0716-3032-7_25
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Publisher Name: Humana, New York, NY
Print ISBN: 978-1-0716-3031-0
Online ISBN: 978-1-0716-3032-7
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