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Lab-on-a-Chip Immunoassay for Prediction of Severe COVID-19 Disease

Part of the Methods in Molecular Biology book series (MIMB,volume 2511)


Most people infected by the SARS-CoV-2 virus which causes COVID-19 disease experience mild or no symptoms. Severe forms of the disease are often marked by a hyper-inflammatory response known as a cytokine storm. Thus, biomarker tests which can identify these patients and place them on the appropriate treatment regime at the earliest possible phase would help to improve outcomes. Here we describe an automated microarray-based immunoassay using the Fraunhofer lab-on-a-chip platform for analysis of C-reactive protein due to its role in the hyper-inflammatory response.

Key words

  • COVID-19
  • SARS-CoV-2
  • Cytokine storm
  • Biomarker
  • Lab-on-a-chip
  • LOC

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Correspondence to Harald Peter .

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Peter, H., Mattig, E., Guest, P.C., Bier, F.F. (2022). Lab-on-a-Chip Immunoassay for Prediction of Severe COVID-19 Disease. In: Guest, P.C. (eds) Multiplex Biomarker Techniques. Methods in Molecular Biology, vol 2511. Humana, New York, NY.

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  • Print ISBN: 978-1-0716-2394-7

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