Abstract
Gut microbiota plays an essential role in gut–brain interactions. From insect to mammals, studies using germ-free animals have demonstrated that indigenous host microbes influence emotional activities, stress, and sexual behaviors. In addition, microbes appear to govern human mental disorders such as autism and depression. Bacterial infections of the gut also influence host behaviors. For example, food poisoning causes the cessation of food intake behavior. Interestingly, intestinal parasites facilitate their transmission by manipulating host behaviors. However, the underlying mechanisms of how gut microbes modulate brain functions remain to be elucidated. Drosophila melanogaster is an effective animal model in neurobiology, particularly the genetic dissection of instinctive behaviors. Here, we provide detailed methods of working with gut bacteria—endogenous as well as infectious—for Drosophila neurobiologists who are interested in microbiology.
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Kadoguchi, H., Hori, A., Kuraishi, T. (2022). Gut Microbes and Drosophila Behavior. In: Yamamoto, D. (eds) Behavioral Neurogenetics. Neuromethods, vol 181. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2321-3_5
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DOI: https://doi.org/10.1007/978-1-0716-2321-3_5
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