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Methods to Detect NF-κB Activity in Tumor-Associated Macrophage (TAM) Populations

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NF-κB Transcription Factors

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2366))

Abstract

Macrophages are an abundant population in the tumor-infiltrating immune cells. The transcription factor NF-κB plays an important role in the response of tumor-associated macrophages (TAMs) to the tumor environmental cues. Detecting NF-κB activity in TAMs will help define the functional status of the TAMs. In this article, we describe several methods to detect NF-κB activity in TAM populations.

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Correspondence to Zhaoxia Qu or Gutian Xiao .

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Sun, F., Qu, Z., Xiao, G. (2021). Methods to Detect NF-κB Activity in Tumor-Associated Macrophage (TAM) Populations. In: Franzoso, G., Zazzeroni, F. (eds) NF-κB Transcription Factors. Methods in Molecular Biology, vol 2366. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1669-7_13

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  • DOI: https://doi.org/10.1007/978-1-0716-1669-7_13

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1668-0

  • Online ISBN: 978-1-0716-1669-7

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