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Evaluation of Antimicrobial and Anticancer Activities of Bouea macrophylla Ethanol Extract

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Physical Exercise and Natural and Synthetic Products in Health and Disease

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2343))

Abstract

The Bouea macrophylla (B. macrophylla) tree is widely grown throughout South East Asia and has been used as a traditional medicine for the treatment of various illnesses. This chapter presents a protocol for preparation of ethanol extracts of B. macrophylla leaves and evaluation of the potential antimicrobial and anticancer activities in vitro. The extract displayed antibacterial activity against nine out of the ten target microorganisms tested. In addition, the extract was capable of inhibiting the proliferation of HeLa and HCT116 cells, thus demonstrating some anticancer activity.

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Author information

Authors and Affiliations

  1. Department of Biomedical Engineering, School of Medicine, Vietnam National University – Ho Chi Minh City (VNU-HCM), Ho Chi Minh City, Vietnam

    Giau Van Vo

  2. Research Center for Genetics and Reproductive Health, School of Medicine, Vietnam National University – Ho Chi Minh City (VNU-HCM), Ho Chi Minh City, Vietnam

    Giau Van Vo

  3. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil

    Paul C. Guest

  4. CirTech Institute, Ho Chi Minh City University of Technology (HUTECH), Ho Chi Minh City, Vietnam

    Ngoc Hong Nguyen

Authors
  1. Giau Van Vo
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  2. Paul C. Guest
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  3. Ngoc Hong Nguyen
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Corresponding authors

Correspondence to Giau Van Vo or Ngoc Hong Nguyen .

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Editors and Affiliations

  1. Charlesworth House, Debden, Essex, UK

    Paul C. Guest

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Van Vo, G., Guest, P.C., Nguyen, N.H. (2022). Evaluation of Antimicrobial and Anticancer Activities of Bouea macrophylla Ethanol Extract . In: Guest, P.C. (eds) Physical Exercise and Natural and Synthetic Products in Health and Disease. Methods in Molecular Biology, vol 2343. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1558-4_14

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  • DOI: https://doi.org/10.1007/978-1-0716-1558-4_14

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1557-7

  • Online ISBN: 978-1-0716-1558-4

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