Abstract
Recent advances in stem cell technologies and tissue engineering are enabling the fabrication of dynamically beating cardiac tissues from human induced pluripotent stem cells. These engineered human cardiac tissues are expected to be used for cardiac regenerative therapies, in vitro drug testing, and pathological investigations. Here we describe the method to fabricate engineered cardiac tissues from human induced pluripotent stem cell-derived cardiomyocytes and to measure the contractile force.
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Acknowledgment
This work was supported by Japan Agency for Medical Research and Development (AMED, https://www.amed.go.jp/en/index.html) under Grant Number JP18im0302706.
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Sasaki, D., Matsuura, K., Shimizu, T. (2021). Contractile Force Measurement of Engineered Cardiac Tissues Derived from Human iPS Cells. In: Yoshida, Y. (eds) Pluripotent Stem-Cell Derived Cardiomyocytes. Methods in Molecular Biology, vol 2320. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1484-6_16
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DOI: https://doi.org/10.1007/978-1-0716-1484-6_16
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Publisher Name: Humana, New York, NY
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Online ISBN: 978-1-0716-1484-6
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