Abstract
Processing, storing, and visualizing high-resolution Hi-C data required development of efficient data formats. A sparse matrix format saving only nonzero values has become the norm. A “zoomable” matrix style also became popular, storing multiple resolutions in a single file for interactive visualization. This chapter discusses the latest matrix file formats such as .hic and .mcool, and other intermediate formats including SAM/BAM and random-accessible contact lists.
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Lee, S. (2022). Hi-C Data Formats. In: Bicciato, S., Ferrari, F. (eds) Hi-C Data Analysis. Methods in Molecular Biology, vol 2301. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1390-0_6
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DOI: https://doi.org/10.1007/978-1-0716-1390-0_6
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