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Sample Preparation for Proteomic Analysis of Cerebrospinal Fluid

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Cerebrospinal Fluid Biomarkers

Part of the book series: Neuromethods ((NM,volume 168))

Abstract

This protocol describes sample preparation of CSF for proteomic analysis by LC-MS . The protocol can optionally be used in conjunction with quantification by the tandem mass tag (TMT) technique, which due to its high multiplexing capability is particularly useful in discovery proteomic studies when large cohorts are to be analyzed.

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References

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Correspondence to Johan Gobom .

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Gobom, J. (2021). Sample Preparation for Proteomic Analysis of Cerebrospinal Fluid. In: Teunissen, C.E., Zetterberg, H. (eds) Cerebrospinal Fluid Biomarkers. Neuromethods, vol 168. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1319-1_11

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  • DOI: https://doi.org/10.1007/978-1-0716-1319-1_11

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1318-4

  • Online ISBN: 978-1-0716-1319-1

  • eBook Packages: Springer Protocols

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