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Translational Research in Neuroimmunology: Cognition

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Translational Methods for Multiple Sclerosis Research

Part of the book series: Neuromethods ((NM,volume 166))

Abstract

Cognitive impairment affects up to 70% of patients with multiple sclerosis (MS). It may already be present in the early stages of disease and impedes with a patient’s ability to maintain employment, take part in activities of daily life, and fully participate in society. Similar to the clinical heterogeneity of MS , there is great variability in cognitive symptoms among patients. Given the impact of such deficits on everyday functioning, an increasing interest in diagnosis and treatment of cognitive impairment has arisen.

This chapter aims to present an overview of those cognitive domains most commonly affected in MS , common approaches to assess the respective cognitive functions as well as procedures which may facilitate cross-species study of cognition.

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Author information

Authors and Affiliations

  1. Department of Neurology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany

    Maren Person

  2. Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands

    Miriam Becke

Authors
  1. Maren Person
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  2. Miriam Becke
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Correspondence to Maren Person .

Editor information

Editors and Affiliations

  1. Department of Neurology and Neuroimaging Center (NIC) of the Focus Program Translational Neuroscience (FTN), University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany

    Sergiu Groppa

  2. Department of Neurology, University of Düsseldorf, Düsseldorf, Germany

    Sven G. Meuth

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Person, M., Becke, M. (2021). Translational Research in Neuroimmunology: Cognition. In: Groppa, S., G. Meuth, S. (eds) Translational Methods for Multiple Sclerosis Research. Neuromethods, vol 166. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1213-2_12

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  • DOI: https://doi.org/10.1007/978-1-0716-1213-2_12

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1212-5

  • Online ISBN: 978-1-0716-1213-2

  • eBook Packages: Springer Protocols

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