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The Brain Reward System pp 263–278Cite as

Conditioned Place Preference Test for Assessing the Rewarding Effects of Drugs of Abuse

Part of the Neuromethods book series (NM,volume 165)

Abstract

The conditioned place preference (CPP) procedure is used for assessing the rewarding effects of drugs. This is demonstrated when a novel environment becomes associated with a drug’s effects, to the extent that an organism, when given the choice, will prefer to be in that environment. The procedure has been used across numerous drug classes and species. This chapter reviews the approaches to conducting CPP studies, including considerations on equipment setups, training procedures, data analyses, pharmacological manipulations, conditioned place aversion, and other features of place conditioning. The chapter serves as a primer for using this procedure for the study of drugs that produce rewarding or aversive effects.

Key words

  • Conditioned place preference
  • Drug
  • Motivation
  • Reward

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Acknowledgments

The authors wish to thank Joseph Porter (Virginia Commonwealth University) for providing images of his place conditioning equipment (Fig. 1) and John Traynor (University of Michigan) for providing unpublished data for CPP (Figs. 2 and 3).

Author information

Authors and Affiliations

  1. Department of Psychology, University of Wisconsin Green Bay, Green Bay, WI, USA

    Todd Hillhouse

  2. Department of Psychological Science, Northern Michigan University, Marquette, MI, USA

    Adam Prus

Authors
  1. Todd Hillhouse
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  2. Adam Prus
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Correspondence to Adam Prus .

Editor information

Editors and Affiliations

  1. Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Beirut, Lebanon

    Marc Fakhoury

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Hillhouse, T., Prus, A. (2021). Conditioned Place Preference Test for Assessing the Rewarding Effects of Drugs of Abuse. In: Fakhoury, M. (eds) The Brain Reward System. Neuromethods, vol 165. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1146-3_13

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  • DOI: https://doi.org/10.1007/978-1-0716-1146-3_13

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